Lecture Shedule

1 Synthesis of nonessential amino acids. Individual transformations of amino acids. Decarboxylation of amino acids. Biogenic amines: histamine, serotonin, γ-aminobutyric acid. Deamination and hydroxylation of biogenic amines. Amino acids as sources of carbon and nitrogen in the synthesis of mononucleotides.

2 Matrix biosynthesis. Nucleic acids are carriers of genetic information. Relationship between structure and function. Replication, repair and recombination of DNA. RNA transcription and processing. Translation and post-translational protein modification.

3 The main systems of intercellular communication. Classification of hormones. Target cells and cellular hormone receptors.

4 Regulation of energy metabolism. The role of insulin and contra insular hormones in homeostasis. Changes in hormonal status and metabolism in diabetes mellitus. The role of hormones in the regulation of calcium and phosphate metabolism (parathyroid hormone, calcitonin and calcitriol).

5 Biochemistry of connective tissue. Cellular composition. Intercellular matrix. Structure and functions of connective tissue.

6 Biochemistry of bone tissue. Cellular composition. Mineral composition of bone tissue. Bone proteins. Bone tissue remodeling.

7 Biochemistry of the tooth. Types of tooth tissues. Organic and mineral phases of tooth tissues.

8 Biochemistry of the oral fluid. Physicochemical properties of saliva. Saliva proteins. Enzymes of saliva. Inorganic substances of saliva. Protective systems of saliva.

9 Biochemical markers of bone metabolism.

Last modified: Saturday, 22 August 2020, 8:50 PM